SFB 749 Publications

Research Area A

  NMR Structure of a Monomeric Intermediate on the Evolutionary Optimized Assembly Pathway of a Small Trimerization Domain
  Increasing the efficiency of the ring-opening reaction of photochromic indolylfulgides by optical pre-excitation
  An unlocking/relocking barrier in conformational fluctuations in villin headpiece subdomain
  Nanostructured Silica Materials As Drug-Delivery Systems for Doxorubicin: Single Molecule and Cellular Studies
  An Unfolded CH1 Domain Controls the Assembly and Secretion of IgG Antibodies
  beta-Lactam Probes As Selective Chemical-Proteomic Tools for the Identification and Functional Characterization of Resistance Associated Enzymes in MRSA
  Thymine Dimerization in DNA Model Systems: Cyclobutane Photolesion Is Predominantly Formed via the Singlet Channel
  Accelerated and Efficient Photochemistry From Higher Excited Electronic States in Fulgide Molecules
  Structurally Refined b-Lactones as Potent Inhibitors of Devastating Bacterial Virulence Factors
  Local conformational dynamics in alpha-helices measured by fast triplet transfer
  Beta-Lactones as Specific Inhibitors of ClpP Attenuate the Production of Extracellular Virulence Factors of Staphylococcus aureus
  Beta-Lactams as Selective Chemical Probes for the in Vivo Labeling of Bacterial Enzymes Involved in Cell Wall Biosynthesis, Antibiotic Resistance, and Virulence
  The structure of a folding intermediate provides insight into differences in immunoglobulin amyloidogenicity
  beta-Lactones as Privileged Structures for the Active-Site Labeling of Versatile Bacterial Enzyme Classes
  Ultrafast Ring-Closure Reaction of Photochromic Indolylfulgimides Studied with
  Ultrafast dynamics and temperature effects on the quantum efficiency of the ring-opening reaction of a photochromic indolylfulgide
  Chemical control of Hemithioindigo-photoisomerization – Substituent-effects on different molecular parts
  Ultrafast reaction dynamics of the complete photo cycle of an indolylfulgimide studied by absorption, fluorescence and vibrational spectroscopy
  Diffusion of Oriented Single Molecules with Switchable Mobility in Networks of Long Unidimensional Nanochannels
  Dissecting the Differences between the a and b Anomers of the Oxidative DNA Lesion FaPydG
  Selective Detection of 5-Methylcytosine Sites in DNA
  Copper Free "Click" Modification of DNA via Nitrile Oxide-Norbornene 1,3-Dipolar Cycloaddition
  Novel Diazirine-Containing DNA Photoaffinity Probes for the Investigation of DNA-Protein-Interactions
  Once Overlooked, Now Made Visible: ATL Proteins and DNA Repair
  Controlled Nucleation of DNA Metallization
  Synthesis of Threefold Glycosylated Proteins using Click Chemistry and Genetically Encoded Unnatural Amino Acids
  The archaeal cofactor F0 is a light-harvesting antenna chromophore in eukaryotes
  Crystal structure analysis of DNA lesion repair and tolernce mechanisms

Research Area B

  Ein programmierbares, DNA-basiertes molekulares Ventil für kolloidales, mesoporöses Siliciumoxid
  Oxidation State, Aggregation, and Heterolytic Dissociation of Allyl Indium Reagents
  Nucleophilicity and Nucleofugality of Phenylsulfinate (PhSO2−): A Key to Understanding its Ambident Reactivity
  A Highly Charged Ag6 4+ Core in a DNA-Encapsulated Silver Nanocluster
  Carbocationic n-endo-trig Cyclizations
  Structure-Reactivity Relationships in Negishi Cross-Coupling Reactions
  Synthesis and Characterization of Novel Quinone Methides: Reference Electrophiles for the Construction of Nucleophilicity Scales
  Microsolvated and Chelated Butylzinc Cations: Formation, Relative Stability, and Unimolecular Gas-Phase Chemistry
  Kinetics of Bromine-Magnesium Exchange Reactions in Heteroaryl Bromides
  The Key Role of Salvation Dynamics in Intramolecular Electron Transfer: Time-Resolved Photophysics of Crystal Violet Lactone
  Kinetics of Bromine#Magnesium Exchange Reactions in Substituted Bromobenzenes
  Nucleophilicities of the Anions of Arylacetonitriles and Arylpropionitriles in Dimethyl Sulfoxide
  Nucleophilic Reactivities of Azulene and Fulvenes
  Formation of Organozincate Anions in LiCl-Mediated Zinc Insertion Reactions
  Negishi Cross-Couplings Compatible with Unprotected Amide Functions
  Nucleophilicity Parameters for Phosphoryl-Stabilized Carbanions and Phosphorus Ylides: Implications for Wittig and Related Olefination Reactions
  Aggregation and Reactivity of Organozincate Anions Probed by Electrospray Mass Spectrometry
  Negishi Cross-Couplings of Unsaturated Halides Bearing Relatively Acidic Hydrogen Atoms with Organozinc Reagents
  Reactions of Nitroheteroarenes with Carbanions: Bridging Aromatic, Heteroaromatic, and Vinylic Electrophilicity
  Ambident Reactivity of the Cyanate Anion
  Regio- and Stereoselective Ring-Opening Reactions of Epoxides with Indoles and Pyrroles in 2,2,2-Trifluoroethanol
  Relative Rates of Bromine-Magnesium Exchange Reactions in Substituted Bromobenzene Derivatives
  Relative Geschwindigkeiten der Brom-Magnesium-Austauschreaktionen
  Copper(I)-Mediated Oxidative Cross-Coupling between Functionalized Alkynyl Lithium and Aryl Magnesium Reagents

Research Area C

  Radicals in enzymatic catalysis— a thermodynamic perspective
  Ab Initio Studies on the Photophysics of Guanine Tautomers: Out-of-Plane Deformation and NH Dissociation Pathways to Conical Intersections
  Nonradiative Decay Mechanisms of the Biologically Relevant Tautomer of Guanine
  Accelerated and Efficient Photochemistry From Higher Excited Electronic States in Fulgide Molecules
  Efficiency reduction and pseudo-convergence in replica exchange sampling of peptide folding-unfolding equilibria
  Ultrafast dissociation pathways of diphenylmethyl chloride to generate reactive carbo cations
  The polarizability of point-polarizable water models: DFT/MM results
  Optimal temperature ladders in replica exchange simulations
  Efficieny of exchange schemes in replica exchange
  Simulated solute tempering
  The "Hot-Solvent/Cold-Solute" Problem Revisited
  Polarization effects stabilize bacteriorhodopsin's chromophore binding pocket: A molecular dynamics study




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