For the improvement of chemical reactions and the understanding of chemical and biochemical processes an investigation of the dynamic parameters of molecules and biomolecules of chemical transformations becomes increasingly necessary. Proteins fold slowly along different folding paths into their active conformation. Enzymes speed up reactions along defined reaction trails, and chemical transformations proceed over active complexes or reactive intermediates, which form in solution time-dependent out of the educts. The investigation of the structure of the reactive intermediates as well as the time flow of chemical and biochemical transformations requires a alliance of chemistry and biochemistry with theoretical chemistry on the one hand and on the other the comprehension of time-resolved measuring methods, which are developed in physics. The researchers of the Collaborative Research Center 749 Dynamics and Intermediates of Molecular Transformations SFB749 want to investigate this processes with the help of state-of-the-art ultra-short time methods and most accurate theoretical processes.

The SFB749 is located in and around munich. Most of our reseachers are members of the Ludwig-Maximilians-Universität LMU from the departments of chemistry, biology and physics. Other members come from the Technischen Universität München TUM and the Max Planck Institute for Medical Research in Heidelberg.

Research in the SFB749 is defined in three research areas:

- A: Dynamics and Intermediates of biochemical transformations

- B: Dynamics and Intermediates of chemical transformations

- C: Theoretical treatment of the dynamics of molecular transformations

The SFB749 holds a close collaboration with the Center for integrated Protein Science Munich CIPSM, an excellence cluster of the first round of the German Excellence Initiative.